亚海生物科技有限公司
YA HAI BIOTECHNOLOGY LTD

医药化工Pharmaceutical Chemical

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The pharmaceutical industry is not only aimed at safeguarding public health but also crucial for the development of the national economy. Substances extracted from natural minerals, plants, and animals, as well as those synthesized chemically or biologically, are collectively referred to as chemical drugs. These drugs possess well-defined structures and exhibit preventive, therapeutic, and diagnostic properties, or are used to regulate bodily functions, enhance quality of life, and maintain physical well-being. Chemical drugs are based on chemical compounds as their material foundation and rely on their pharmacological effects (biological responses) for their applications.

With the rapid development of the global economy and technological advancements, the production of fine chemical products and chemical raw materials for pharmaceuticals has entered a mature stage. Since the beginning of the 21st century, the progress in medicine cannot be achieved solely through general technological advancements; instead, it heavily relies on new breakthroughs in scientific technology. So far, there are over 10 million globally synthesized compounds, with the sales of fine chemicals reaching $50 billion, growing at an annual rate of approximately 5%. Within this sector, pharmaceutical intermediates and chemical raw materials dominate. The chemical raw materials industry serves as a crucial foundation for the pharmaceutical industry, with over 2,000 types of raw materials drugs produced worldwide. The market size expanded from nearly $10 billion in 1996 to $13 billion in 2000, with an annual growth rate of around 7%. Approximately 60% of the chemical raw materials and intermediates required by foreign pharmaceutical manufacturers are obtained through outsourcing or contract manufacturing.

分子检测Molecular Detection

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Molecular detection is the use of molecular biology techniques to test and analyze nucleic acid substances in body fluids, blood, tissues, and other samples. The application of molecular detection technology in in vitro diagnostics is referred to as molecular diagnostics, which is currently the fastest developing and most cutting-edge direction in the field of in vitro diagnostics. In addition to disease diagnosis, research institutes, pharmaceutical companies, CROs, and others also use molecular detection technology and products for research and development work. Molecular diagnostics refers to the use of molecular biology methods to detect changes in the structure or expression levels of genetic material in the patient's body for diagnostic purposes. Specifically, by analyzing the expression of DNA, RNA, or proteins, identifying abnormalities or variations in the genetic code, or determining the presence of specific genes, it is possible to determine the susceptibility or presence of a disease and provide this information to healthcare providers for risk assessment, diagnosis, prognosis, and treatment.

分子工具Molecular Tool

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Viral vectors are the main gene delivery tools used in emerging therapies such as cell therapy and gene therapy (Cell & Gene Therapy, CGT). Viral vectors are one of the most important gene transfer tools in biomedical research, commonly used in gene therapy, cell therapy research, and drug development. The production of viral vectors accounts for more than one-third of the R&D costs in CGT. Viral vectors include adeno-associated viruses (AAV), adenoviruses, lentiviruses, and others. AAV and lentiviral vectors (LV) are the two most widely used viral vectors, with AAV being more commonly used in gene therapy and LV being the primary vector for CAR-T therapy. AAV vectors have advantages such as organ targeting, high safety, and long-lasting effects, but they also have the drawback of limited payload capacity. LV vectors can transfer target genes into cells in vitro, where these genes integrate into the chromosomes and can be expressed long-term in vivo, offering advantages such as high safety. However, there are potential risks, such as insertional mutagenesis and carcinogenicity. These two types of viral vectors are the main vectors used in gene therapy and cell therapy, respectively.

公司简介 Company Profile
YaHai Bio

Yahai Biotechnology Company is a technology promotion and application service enterprise, mainly engaged in the following projects: medical research and experimental development, cell technology research and application, new material technology research and development, new material technology promotion services, engineering and technical research and experimental development, sales of Class I medical devices, health consultation services (excluding diagnosis and treatment services), sales of chemical products (excluding licensed chemical products), sales of electronic special materials, research and development of electronic special materials, wholesale and retail of cosmetics, agricultural science research and experimental development, natural science research and experimental development, sales of specialty chemicals (excluding hazardous chemicals), software development, sales of water quality pollutants monitoring and testing instruments, sales of ecological environment monitoring and testing instruments, human gene diagnosis and treatment technology development, technical services, technical development, technical consulting, technical exchanges, technology transfer, and technology promotion.

Yahai Biotechnology is dedicated to exploring the application of cutting-edge molecular biology technology and pharmaceutical and chemical engineering in the fields of life science research and human health, and is committed to becoming a global producer and service provider of biological products. Yahai Biotechnology's business covers the fields of biomedicine, gene research (siRNA, mimics), animal models, pharmaceutical and chemical raw materials, and DNA testing. It provides molecular tools, gene sequencing, and biological information technology support services to global research universities, research institutes, hospitals, pharmaceutical research and development companies, and agricultural enterprises. Based on a complete molecular pathological testing platform, tumor detection provides accurate solid tumor molecular pathological testing products and services for patients, hospitals, and pharmaceutical companies. Molecular tool preparation and deep gene sequencing and big data analysis interpretation are the core services. Yahai Biotechnology continues to develop international tumor gene detection products and molecular therapeutic products, and provides accurate tumor treatment solutions such as tumor medication guidance, dynamic monitoring, and genetic susceptibility gene testing. In terms of genetic testing, Yahai Biotechnology has developed a series of detection services based on second-generation sequencing technology, including prenatal genetic testing, neonatal genetic screening, personal genome and other products, and has explored the application of genomics in the field of human health, used for reproductive health and personal genomics, and provides professional genetic counseling services to clients.

生物医药 Biomedical Pharmaceuticals
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Inflammatorybowel disease (IBD) is a chronic inflammatory condition that affects theintestine. Environmental factors, infectious microbes,genetic susceptibility,and a dysregulated immune system can...

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Introduction.Oncolytic virotherapy is a promising cancer treatment that usesreplication-competent viruses to induce cancer cell death.While clinical trialsare underway for a variety of solid tumors...

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少有人知的细胞外基质(ECM)和免疫系统对话大家都知道,疾病的局部免疫微环境和细胞外基质(ECM)正日益受到越来越多学者的关注,尤其是在肿瘤研究中,免疫和ECM无疑都是医学领域科研和国自然申请的热点。然而,你是否知道,免疫细胞和ECM之间也会有互相作用和调控的关系?今天笔者分享的是2023年2月发表于Science(IF:63.714)上的综述文章:细胞外基质与免疫系统:相互依赖的关系。长期...

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无创孕期亲子检测Non-invasive Prenatal Paternity Test孕妇外周血中存在胎儿遗传物质•妊娠第5周开始母血血浆可检出胎儿cfDNA,分娩后2h之内消失• 孕周12周之后胎儿cfDNA比例约占5%,但存在个体差异• 胎儿cfDNA呈高度碎片化,长度集中在170bp左右•对母体外周血中血浆游离DNA测序分析,获得胎儿遗传信息,进而判定亲子关系。• 对孕妈和胎儿无任何...

YAHAI Pharmaceuticals
YAHAI Pharmaceuticals

Yahai Pharmaceuticals is a leading pharmaceutical company dedicated to the research, development, production, and sale of high-quality medical products. As an innovation-driven company, Yahai Pharmaceuticals is committed to meeting the medical needs of patients worldwide and continuously driving advancements in the pharmaceutical field.

As a pharmaceutical company with advanced technology and facilities, Yahai Pharmaceuticals possesses exceptional capabilities in drug research and development and production. We have an experienced team of researchers focused on the discovery and development of new drugs. Through continuous innovation and collaboration, we strive to develop innovative drugs for severe diseases and improve the quality of life for patients worldwide.

Yahai Pharmaceuticals' manufacturing facilities comply with international pharmaceutical quality standards and adhere to strict quality control systems. We employ advanced production processes and equipment to ensure the quality and purity of our products. Our production line covers a wide range of medication categories, including prescription drugs, over-the-counter drugs, and biologics, to meet the needs of different markets and patients.

As a responsible pharmaceutical company, Yahai Pharmaceuticals places a strong emphasis on the safety and efficacy of medications. We strictly adhere to regulations and ethical requirements and are committed to promoting accessibility and affordability of medications. We collaborate with global partners to ensure widespread promotion and use of our products on a global scale.

Yahai Pharmaceuticals is also dedicated to engaging in social responsibility activities and actively participating in charitable and medical assistance projects. We support community health initiatives, provide education and training opportunities, and strive to improve the accessibility and sustainability of global healthcare.

Through continuous innovation and dedication, Yahai Pharmaceuticals aims to become a global leader in the pharmaceutical industry, providing high-quality, safe, and effective medications to patients worldwide, and improving human health and quality of life. We will continue to strive for greater contributions to the progress and development of the pharmaceutical industry.

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项目Item
微小残留病灶血液肿瘤检测HEME-MRD Detection
微小残留病灶血液肿瘤检测HEME-MRD Detection
微小残留病灶血液肿瘤检测Hematologic Malignancies Minimal Residual Disease DetectionThe HEME-MRD detection method is typically used after the completion of cancer treatment to determine if a patient has achieved complete remission. If the HEME-MRD test result is negative, it indicates that the patient has a good prognosis and a lower risk of relapse. If the HEME-MRD test result is positive, it suggests that the patient may require longer or more intensive treatment to achieve complete remission and reduce the risk of relapse. The HEME-MRD detection method is an important tool for monitoring the progress of hematologic malignancies and improving treatment outcomes.Hematologic malignancies, such as leukemia and lymphoma, are cancers that affect the blood, bone marrow, and lymphatic system. These cancers are typically diagnosed based on a combination of symptoms, physical examination, and laboratory tests, including blood tests, bone marrow biopsy, and imaging studies.After a patient with a hematologic malignancy receives treatment, such as chemotherapy or radiation therapy, it is important to monitor the patient's response to treatment and the risk of disease recurrence. The HEME-MRD detection method is a highly sensitive way to detect the small number of residual cancer cells that may be present in the body after treatment.The HEME-MRD detection method can be used to monitor a patient's response to treatment and to predict the risk of disease recurrence. For example, if a patient with leukemia has a positive HEME-MRD test result after treatment, it suggests that there may still be cancer cells present in the body, and the patient may require additional treatment to achieve complete remission. On the other hand, if a patient with lymphoma has a negative HEME-MRD test result after treatment, it suggests that the patient has a lower risk of disease recurrence and a better prognosis.The HEME-MRD detection method is a valuable tool for guiding treatment decisions and improving outcomes in patients with hematologic malignancies. By detecting residual cancer cells early, clinicians can adjust their treatment strategies and tailor the patient's care to their individual needs.