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少有人知的细胞外基质(ECM)和免疫系统对话大家都知道,疾病的局部免疫微环境和细胞外基质(ECM)正日益受到越来越多学者的关注,尤其是在肿瘤研究中,免疫和ECM无疑都是医学领域科研和国自然申请的热点。然而,你是否知道,免疫细胞和ECM之间也会有互相作用和调控的关系?今天笔者分享的是2023年2月发表于Science(IF:63.714)上的综述文章:细胞外基质与免疫系统:相互依赖的关系。长期...
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Inflammatorybowel disease (IBD) is a chronic inflammatory condition that affects theintestine. Environmental factors, infectious microbes,genetic susceptibility,and a dysregulated immune system can...
原料药Raw Materials
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Raw materials are chemical substances or other materials required in the pharmaceutical manufacturing process, and their function is to produce various drugs. Raw materials are an important component of the pharmaceutical industry and one of the core competitiveness of pharmaceutical companies. The quality and stability of raw materials have a crucial impact on the quality, safety, and efficacy of drugs.

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Raw materials can come from nature or be obtained through chemical synthesis and other methods. Natural raw materials include plants, animals, and microorganisms. For example, artemisinin is extracted from the Artemisia annua plant, and streptomycin is synthesized from Streptomyces. Chemically synthesized raw materials are synthesized from raw materials through a series of chemical reactions. For example, aspirin is obtained through chemical modification of salicylic acid.

The production process of raw materials usually includes several steps: raw material procurement, drug production, drug quality control, and drug packaging. In the raw material procurement stage, pharmaceutical companies need to choose high-quality raw material suppliers to ensure the quality and stability of raw materials. In the drug production stage, raw materials are mixed with other excipients and processed through a series of processes to finally produce drugs. In the drug quality control stage, pharmaceutical companies need to test the quality of raw materials and drugs to ensure that drugs comply with relevant national standards and requirements. In the drug packaging stage, drugs need to be packaged to ensure their quality and safety.

The quality and stability of raw materials have a crucial impact on the efficacy and safety of drugs. Therefore, pharmaceutical companies need to strictly control the quality and stability of raw materials to ensure the quality and safety of drugs. At the same time, pharmaceutical companies need to continuously strengthen technological innovation, improve the production efficiency and quality of raw materials, and further improve the efficacy and safety of drugs.

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In summary, raw materials are an important component of the pharmaceutical industry and one of the core competitiveness of pharmaceutical companies. Pharmaceutical companies need to strictly control the quality and stability of raw materials, continuously strengthen technological innovation, improve the production efficiency and quality of raw materials to ensure the quality and safety of drugs.


Pharmaceutical Chemical
Raw materials

1.Enoxaparin Sodium  CAS:9041-08-1

2.Sodium Hyaluronate  CAS:9067-32-7

3.Levofloxacin Hemihydrate  CAS:138199-71-0

4.Ibuprofen   CAS:15687-27-1

5.Azithromycin Dihydrate  CAS:117772-70-0

6.Ivermectin   CAS:70288-86-7

7.Praziquantel   CAS:55268-74-1

8.Fenbendazole CAS:43210-67-9

9.Thymoquinone  CAS:490-91-5

10.Imidocarb dipropionate  CAS:55750-06-6

11.Lorcaserin hydrochloride   CAS:  1431697-94-7

12. R-Lorcaserin hydrochloride hemihydrate     CAS:856681-05-5

13.Cetilistat     CAS:282526-98-1

14.Tadalafil  CAS:171596-29-5

15.Tadalafil Derivative   (1R,3R)- methyl -1,2,3,4-tetrahydro-1-(3,4- methylenedioxyphenyl)-9H-pyrido [3,4-B]indole-3-carboxylate   CAS:171489-59-1

16.3-O-Ethyl-L-ascorbic acid 86404-04-8 Crisaborole   CAS: 906673-24-3

17. (1R,3R)-METHYL-1,2,3,4-TETRAHYDRO-1-(3,4-METHYLENEDIOXYPHENYL)-9H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLATE   CAS:171596-41-1

18. Ibudilast   CAS:50847-11-5

19.5-Hydroxy-3,4-dihydroquinolin-2(1H)-one    CAS:30389-33-4

20.Methyl 3-cyclopropyl-3-oxopropanoate 32249-35-7 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER   CAS:571188-82-4

21.5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine    CAS: 733039-20-8